The viral oncogene Np9 acts as a critical molecular switch for co-activating β-catenin, ERK, Akt and Notch1 and promoting the growth of human leukemia stem/progenitor cells

Tianhui Chen,Zhipeng Meng,Yichao Gan,Xiaoqiong Wang,F. Xu,Y Gu,Xiaohua Xu,Jinfen Tang,Hong Zhou,X. Zhang,X Gan,C Van Ness,G. Xu,L Huang,Y. Fang,J. Wu,S. Zheng,Jie Jin,Wendong Huang,Rongzhen Xu

The viral oncogene Np9 acts as a critical molecular switch for co-activating β-catenin, ERK, Akt and Notch1 and promoting the growth of human leukemia stem/progenitor cells

2013

Tianhui Chen
Zhipeng Meng
Yichao Gan
Xiaoqiong Wang
F. Xu
Y Gu
Xiaohua Xu
Jinfen Tang
Hong Zhou
X. Zhang
X Gan
C Van Ness
G. Xu
L Huang
Y. Fang
J. Wu
S. Zheng
Jie Jin
Wendong Huang
Rongzhen Xu

The viral oncogene Np9 acts as a critical molecular switch for co-activating β-catenin, ERK, Akt and Notch1 and promoting the growth of human leukemia stem/progenitor cells

Keywords:

Protein kinase B
Progenitor cell
Promyelocytic leukemia protein
Cancer research
ABL
MAPK/ERK pathway
Cell biology
Cancer stem cell
Viral Oncogene
Biology
Leukemia inhibitory factor receptor

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