Synthesis and characterization of Fe@FePt@SiO2@NH2 nanoplatform for amino acids recognition

The main goal of this work consists of synthesis of new magnetic multifunctional nanoplatforms based on Fe@FePt core, with principal target in applications regarding the capture and separation of amino acids. These expectations were fulfill by attaching amino functional groups on the core surface. Therefore, our Fe@FePt@SiO2@NH2 core-shell nanoparticles could serve as promising multifunctional nanoplatforms for molecular recognition and magnetic separation. In this way, these nanoplatforms are capable to catch the amino acids (lysine, cysteine, and alanine) from liquid media. The properties of the obtained nanoparticles were evaluated, and the retention level was determined by high-performance liquid chromatography. It was found that for a mass ratio of 10 and 40 between nanoparticles and amino acids, the lysine is best retained from liquid media. For a mass ratio of 20, the best level of retention was realized for alanine. The most responsive was the lysine followed by the alanine and then by the cysteine.