Susceptibility for breast cancer in young patients with short rare minisatellite alleles of BORIS

in normal cells induces activation of several cancer-testis genes (MAGE-A1, NY-ESO-1, and others) (2, 5). While the BORIS protein is present at variable levels in the nucleus and the cytoplasm in several breast cancer cell lines, it is not expressed in normal breast cells (4). Moreover, high lev-els of the BORIS protein in the leukocyte fraction of patients with breast cancer was detected, which suggests that