CYCLIC NEUTROPENIA IN A FATHER AND DAUGHTER

Cyclic neutropenia was first reported by Leale 1 in 1910. In 1946, Reimann and de Berardinis 2 collected 13 cases from the literature, reported 1 of their own, and briefly abstracted two others which were previously unpublished. One of the latter is reported here in more detail. Thirteen case reports 3 other than the 16 summarized by Reimann and de Berardinis have appeared in the literature. In none of these has there been any evidence of this entity appearing in more than one member of the family. The subject of this report is two cases of cyclic neutropenia occurring at a young age in a father and daughter. Report of Cases Case 1.— A boy was first seen in 1941 at the age of 14 years. His family stated that he had had furunculosis at the age of 6 weeks and bronchopneumonia at 18 months. Since the age of 2