Endocrine disturbances in circumscribed scleroderma

AIM: To evaluate prevalence of endocrine pathology in patients with circumscribed scleroderma (CS), baseline immunopathological alterations in CS patients. MATERIAL AND METHODS: Circulating immune complexes were studied by the Digeon method in a total of 70 CS patients (female 52, 74.3%; male 18, 25.7%; age 16 to 70 years). RESULTS: Circulating immune complexes assay by Digeon detected evident immune imbalance characteristic for metabolic disturbances of the connective tissue and affection of the endocrine system. CONCLUSION: CS patients need a combined examination including endocrinological and immunological tests.