Observation of Mailuoning Injection Open image in new window treating 46 patients with pregnancy induced hypertension) treating 46 patients with pregnancy induced hypertension

Objective: To observe the effect of treatment of Mailuoning Injection (MI) for pregnancy induced hypertension (PIH).Methods: Forty six PIH patients in the treated group were treated with intravenous dripping of MI and 40 patients in the control group treated with intravenous dripping of 25% magnesium sulfas.Results: Headache and edema were ameliorated significantly in the MI treated group in comparison with the control (P < 0.05). Both methods could the decrease levels of mean arterial pressure, improve hemorheologic change, and lower the hematocrit, but the effects of the former was better than those of the latter. No difference was found in albuminuria, delivery pattern, postpartum bleeding and neonatal Apgar Score between the two groups.Conclusion: MI could prevent the progress of pathological process of the PIH. The therapeutic mechanism of MI might be relevant to the dilatation of the arteriospasm, improvement of the abnormal microcirculation and hemorheologic character of the patients.