Why should we care about fly tumors?: The case of JAK-STAT and EGFR cooperation in oncogenesis
2013
Drosophila is proving to be a valuable model for studying aggressive tumors induced by the combined activation of EGFR and JAK-STAT signaling. Here we summarize some of the most recent data showing that tissue damage and the modulation of common pathway regulators are at the heart tumor progression and metastasis.
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