Apparatus and method for increasing the efficiency of connection capable of binding target structures

Apparatus for increasing the efficiency of connection capable of binding targets, the having a plurality of electromagnets (M1, M2, M3) with which magnetic fields (H1, H2, H3) are over a predetermined period of time can be generated which at least partially magnetic gradient (F1, F2, F3) having increasing magnetic field strength, wherein each electromagnet ( M1, M2, M3) has a core that is shaped in such a way that the poles of (1.1 / 1.2, 2.1 / 2.2, 3.1 / 3.2) of the respective electromagnet (M1, M2, M3) are arranged in pairs opposite each other, with the interposition of a free space (4) is formed, in which the respective magnetic gradient (F1, F2, F3) is formed in regions with increasing field strength, at least, wherein pairwise opposite poles (1.1 / 1.2, 2.1 / 2.2, 3.1 / 3.2) of the plurality of electromagnets (M1, M2, M3) are arranged in vertically superposed horizontal planes, wherein the horizontal planes are positioned vertically above each so that form between the respective horizontal superposed Poland (1.1 / 1.2, 2.1 / 2.2, 3.1 / 3.2) formed free spaces (4) have a common vertical carrying, in the a vessel (5), in the magnetic particles (6) and a liquid, the target containing structures are contained in the common passage between the oppositely arranged poles is (1.1 / 1.2, 2.1 / 2.2, 3.1 / 3.2) so held or arranged such that it at least the area of ​​influence of the magnetic gradient (F1, F2, F3) with increasing magnetic field strength of the magnetic fields (H1, H2, H3) is exposed, wherein the magnetic particles (6) contained therein in the direction of the magnetic gradient (F1, F2, F3) are variable in time can be accelerated, and wherein the magnetic particles (6) have a functionalized surface coating and / or coupling or bonding or immobilizing at least one molecule or molecular moiety represent a bond at least one of present in the liquid target structures.