Food for obesity therapeutics and obesity prevention or improvement

The present invention is treated by activation of PPAR, its prevention, or a disease or condition can improve, in particular insulin-resistant diabetes and hyperlipidemia, treatment, prevention, and compositions for use in improving and food to provide for the purpose. According to the present invention, humulones, isohumulones, or lupulones or those comprising a pharmaceutically acceptable salt or solvate, treated by activation of PPAR, prevention or diseases or conditions can improve, treatment, prevention, or pharmaceutical composition for use in improvement is provided.