DNA Pattern in Oral Cavity Carcinomas in Relation to Clinical Stage and Histological Grading

Summary Cytofluorometric DNA analysis was performed in 88 squamous cell carcinomas of theoral cavity. 48% (42/88) of the tumours were DNA non-diploid. The frequency of DNA non-diploid tumours seemed to correlate with the increasing size of the tumour, and the decrease of histological grading, and certainly with the presence of lymph node metastases (p The S-phase level seemed to increase the less differentiated the tumour but did notcorrelate either to tumour size or to duration of symptoms. Polyploid nuclei were more common in poorly differentiated tumours (9/10) as compared to well differentiated ones (17/33) (p