The MINTAct Archive for Mutations Influencing Molecular Interactions

The MINTAct archive for mutations affecting interaction holds results of over 28,000 events on the influence of a change of protein sequence on physical interaction outcome. All data has been manually curated from experimental evidence found in more than 4,100 publications, following the IMEx consortium (www.imexconsortium.org) high-detail curation standards. The dataset contains data from about 300 different organisms, with a predominance of events related to human proteins, and it is freely available at the IntAct database website using this link: www.ebi.ac.uk/intact/resources/datasets#mutationDs.