A Novel Glucose Biosensor Based on Glucose Oxidase Immobilized on AuPt Nanoparticle – Carbon Nanotube – Ionic Liquid Hybrid Coated Electrode

A novel amperometric glucose biosensor is presented in this article, which is based on the adsorption of glucose oxidase on gold-platinum nanoparticle (AuPt NP)-multiwalled carbon nanotube (MWNT) – ionic liquid (i.e., 1-octyl-3-methylimidazolium hexafluorophosphate, [OMIM]PF6) composite. The gold-platinum nanoparticles is prepared through direct electrodeposition. Owing to the synergistic action of AuPt nanoparticle, MWNT and [OMIM]PF6, the biosensor shows good response to glucose, with wide linear range (0.01 to 9.49 mM), short response time (3 s), and high sensitivity (3.47 μA mM−1). With the biosensor the determination of glucose in human serum is performed.