Distribution and Drug Resistance of Acinetobacter baumannii Isolated from Surgical Intensive Care Unit in 2009

OBJECTIVE To study the distribution and drug resistance of Acinetobacter baumannii from surgical intensive care unit,to provide bases for the rational use of antibiotics in clinics.METHODS A retrospective study on the distribution and drug resistance of A.baumannii in patients of surgical intensive care unit in 2009 was performed.RESULTS A total of 1047 pathogenic bacteria were isolated.Among WHICH,693 isolates(66.2%)were Gram-negative bacteria,156 isolates(14.9%)were Gram-positive bacteria,and 198 isolates(18.9%)were fungi.The most common Gram negative bacteria was A.baumannii and the dominant Gram-positive pathogenic bacteria was Enterococcus faecium.A total of 353 strains of A.baumannii were isolated from 124 cases,among them 197(70.4%)were isolated from respiratory tract,including bronchia(134) and sputum(63),the followings were the wound secretion and abdominal cavity drainage fluid.Drug resistance rates of A.baumannii to the current antibiotics were vary from 66.6% to 99.5% in this study.The drug resistant rate to ceferperozone/sulbactum was the lowest(66.6%),next were meropemem(78.2%) and impenem(79.3%).CONCLUSION The most common infective pathogen in surgical intensive care unit is A.baumannii and mainly isolated from respiratory tract.It is necessary to monitor the pathogen to guide the selection of antibiotics based on the drug sensitive tests.