Protein markers assisting diagnosis of severe secondary pulmonary tuberculosis

The invention discloses protein markers assisting diagnosis of severe secondary pulmonary tuberculosis. The invention provides applications of a product for detecting SOD1 protein, a product for detecting S100A9 protein, a product for detecting ORM2 protein and a product for detecting IL1F6 protein in preparation of a kit used for assisting diagnosis of severe secondary pulmonary tuberculosis. The four protein markers (S100A9, ORM2, IL1F6 and SOD1) assisting diagnosis of the severe secondary pulmonary tuberculosis are found, and a model for assisting diagnosis of the severe secondary pulmonary tuberculosis by utilizing the four protein markers is built. The protein markers provide basis for further explanation of developing and aggravating mechanisms of the secondary pulmonary tuberculosis, provide a novel method and novel indexes for disease development, aggravation early warning, and forecast evaluation, lays a foundation for reasonable treatment and cure of the severe secondary pulmonary tuberculosis, and provides technical supports for reducing the death rate of pulmonary tuberculosis.