Optoelectronic integration of silicon photonic wire biosensors

We review our work developing label-free molecular sensors using silicon nanophotonic waveguides. We show that the high index contrast of these waveguides provides high surface sensitivity and enables compact sensor designs to be realized. We also describe new waveguide circuit geometries that allow photonic wire waveguide sensors to be conveniently arrayed in two dimensions for compatibility with commercial spotting tools, while simultaneously providing long interaction length and improved molecular capture efficiency. These sensor designs are shown to provide a practical route to the development of label-free, microarrayed biochips for multiparameter analysis.