Identification of a CDK4 R24H mutation-positive melanoma family by analysis of early-onset melanoma patients in Latvia.
2009
We have analysed 47 early-onset (≤40 years) Latvian melanoma patients for the involvement of the melanoma susceptibility loci CDKN2A and CDK4. We observed no disease-related mutations in CDKN2A, but one patient had a CDK4 R24H mutation and strong family history of melanoma. Haplotype analysis using
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