Clinical analysis of infected pancreatic necrosis and infected pancreatic necrosis complicated with intestinal fistula

Objective: To investigate the clinical features, diagnosis and treatment as well as outcomes of infected pancreatic necrosis (IPN) and IPN complicated with intestinal fistula. Methods: The clinical data of 33 IPN patients, including 10 cases complicated with intestinal fistula, admitted from January 2010 to December 2014 were retrospectively analyzed. Results: All patients underwent standardized treatment in accordance with acute pancreatitis diagnosis and treatment guideline, and patients with intestinal fistula had additional fistula repair or fistula resection and anastomosis, and peritoneal drainage according to the specific conditions. The mortality of the entire group of 33 patients was 39.4% (13/33), and the severity score (2012) was closely associated with the mortality (P 0.05), but significantly prolonged the hospital stay of the patients (P<0.05). The mortality in patients with intestinal fistula located in uncommon sites (75%, 3/4) was higher than that in patients with intestinal fistula located in common sites (16.7%, 1/6) (P<0.05). ·临床研究· doi:10.3978/j.issn.1005-6947.2015.03.013 http://dx.doi.org/10.3978/j.issn.1005-6947.2015.03.013 Chinese Journal of General Surgery, 2015, 24(3):375–379. 收稿日期:2015-01-08; 修订日期:2015-02-25。 作者简介:潘柏宏,中南大学湘雅医院硕士研究生,主要从事普通外科临床方面的研究。 通信作者:黄耿文, Email: gengwenhuang@outlook.com