The significance of S100B protein, glial fibrillary acidic protein and neuron-specific enolase in premature brain damage

Brain injury in preterm infants is an important reason for making the newborn disability.Neonatal cerebral injury of imaging examination method has a time lag.Looking for a simple, timely, accurate predictor of biological markers of brain injury in preterm infants is particularly important.In this paper, the role of S100B protein, glial fibrillary acidic protein and neuron-specific enolase of brain injury in preterm infants was reviewed, and the significance of early diagnosis of brain injury in preterm infants was discussed. Key words: S100B protein; GIial fibrillary acidic protein; Neuron specific enzyme; Brain injury; Preterm infants