Étude des dommages induits dans l'ADN par irradiation laser X-UV à 21.2 nm

We report the preliminary result of the application of the collisional Ne-like soft x-ray laser as radiation source to induce DNA damage. The goal of this experiment was a test bed study of the damage yields induced by soft x-ray radiation in dried plasmid DNA sample. The saturated Ne-like soft x-ray laser available at the PALS facility, delivering several millijoules in a single 100 ps pulse at 21.2 nm was used to irradiate two different plasmids: pSPl 89 and pBS. The study is centered on the dose effect leading to single and double strand break in DNA.