Environmentally-friendly synthesis method of vitamin E

2013 
The invention relates to the fine chemistry industry synthesis field, and especially relates to an environmentally-friendly synthesis method of vitamin E. The method comprises the following steps: adding 150-200 parts by weight of toluene into a reaction device, sequentially adding 40 parts by weight of 2,3,5-trimethylquinhydrone and 40-80 parts by weight of isophytol under mechanical stirring, slowly adding 1.5-2.5 parts by weight of magnesium chloride and 0.8-1.2 parts by weight of a magnesium oxide supported silica catalyst after the above obtained reaction system is fully dissolved and clear, closing the reaction system, allowing the reaction system to undergo a reaction under a vacuum degree of -0.07 - -0.05MPa at a temperature of 55-65DEG C for 1.5-2.5h, and allowing toluene reflux to be maintained and generated water to be distilled out with the toluene reflux in the reaction to be in favor of the implementation of the reaction; and recovering the catalyst and the above solvent, and carrying out reduced pressure distillation of the solvent-distilled reaction system to obtain a required pale-yellow oily vitamin E product. The method has the advantages of repeated use of the supported catalyst, high yield, low energy consumption and environmental protection.
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