Stable Transfection of a Glypican-1 Antisense Construct Decreases Tumorigenicity in PANC-1 Pancreatic Carcinoma Cells

SummaryGlypican-1 belongs to a family of glycosylphosphatidylinositol (GP1)-anchored heparan sulfate proteoglycans (HSPGs) that affect cell growth, invasion, and adhesion. Cellsurface HSPGs are believed to act as co-receptors for heparinbinding mitogenic growth factors. It was reported that glypican