4CPS-165 Analysis of antibiotic consumption in a nursing home

Background and importance Some studies have concluded that antibiotic consumption in nursing homes is more elevated than in the community. However, in our area, it is not well known. Inappropriate use of antimicrobials is one of the most important problems of drug misuse because it can lead to a major incidence of antimicrobial resistance. Aim and objectives To analyse antibiotic consumption in a nursing home and to compare it with antimicrobial consumption in our community. Material and methods An observational study was carried out from July 2018 to June 2019 in residents of a nursing home (30% dependents and 70% in social exclusion). The variables recorded were number of residents per month, global defined daily dose (DDD) of antibiotics (ATC J01–J02)/1000 residents/days, DDD of amoxicillin–clavulanic acid/1000 residents/day, DDD of quinolones/1000 residents/day and DDD of fosfomycin trometamol/1000 residents/day. These results were compared with the available data from primary care. Results The mean number of residents was 89 (87–101). The global DDD/1000 residents/day was 80.8 (third trimester 2018), 56.5 (fourth trimester 2018), 101.6 (first trimester 2019) and 82.4 (second trimester 2019). The DDD of amoxicillin–clavulanic acid/1000 residents/day was 15.1 (third trimester 2018), 8.4 (fourth trimester 2018), 26.7 (first trimester 2019) and 15.9 (second trimester 2019). The DDD of quinolones/1000 residents/day was 30.4 (third trimester 2018), 13.6 (fourth trimester 2018), 12.6 (first trimester 2019) and 2.8 (second trimester 2019). The DDD of fosfomycin trometamol/1000 residents/day was 1.9 (third trimester 2018), 0 (fourth trimester 2018), 0.6 (first trimester 2019) and 2.3 (second trimester 2019). The global DDD/1000 inhabitants/days in primary care was 14.1 (third trimester 2018), 15.9 (fourth trimester 2018) and 15.4 (first trimester 2019). The DDD of amoxicillin–clavulanic acid/1000 inhabitants/day was 5.5 (third trimester 2018), 5.5 (fourth trimester 2018) and 4.3 (first trimester 2019). The DDD of quinolones/1000 inhabitants/day was 1.2 (third trimester 2018), 1.3 (fourth trimester 2018) and 2.2 (first trimester 2019). The DDD of fosfomycin trometamol/1000 inhabitants/day was 0.4 (third trimester 2018), 0.4 (fourth trimester 2018) and 0.3 (first trimester 2019). Conclusion and relevance Global antibiotic consumption in the nursing home was approximately six times higher than in primary care, mainly due to the prescription of quinolones. Antimicrobial stewardship programmes are necessary to improve the use of antibiotics in this population. References and/or acknowledgements No conflict of interest.