Myocardial characterisation in Becker muscular dystrophy using T1 and T2 mapping

Methods From April 2012 to May 2014, 84 consecutive patients (age=38,6 ± 13,6 years) with Becker muscular dystrophy (BMD) and 12 control subjects underwent cardiac magnetic imaging (MRI) on a 3-T clinical scanner (Magnetom Trio Tim, Siemens Healthcare). T1 maps and apparent extracellular volume fraction (appECV) preand post-GdDOTA injection was performed with a prototype modified Look-Locker sequence (MOLLI, 3, 3 and 5 image acquisitions). T2 maps were generated with a T2 prepared TrueFISP sequence acquired with 3 preparation times (0, 25 and 55 ms). Late Gadolinium enhancement (LGE), T1, T2, appECV were assessed according to the classification of the AHA segmentation.