Novel triazole based inhibitors of Ras farnesyl transferase.
2005
Abstract A novel series of potent inhibitors of Ras farnesyl transferase possessing a 1,2,4-triazole pharmacophore is described. These inhibitors were discovered from a parallel synthesis effort and were subsequently optimized to in vitro IC 50 value of less than 1 nM.
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
28
References
21
Citations
NaN
KQI