TBHP/TFA Mediated Oxidative Cross‐Dehydrogenative Coupling of N‐Heterocycles with Aldehydes.
2016
An effective and metal-free oxidative cross-dehydrogenative coupling (CDC) of N-heterocycles with diverse aldehydes has been established in the presence of TBHP/TFA. The scope with respect to aldehyde and N-heterocycle components is broad, allowing facile synthesis of a broad range of structurally diverse C1-acyl substituted heterocycles in good efficiency.
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