Lichen Planus Pemphigoides -A Case Report-

Lichen planus pemphigoides (LPP) is a rare bullous disorder characterized by bullae on lichen planus like papules and on uninvolved skin. A diagnosis of LPP is made on the basis of clinical, histological, and immunofluorescent evaluation. We describe a 76 year-old patient who developed a vesicular and bullous eruption combined with an efflorescence of lichenoid papules especially on bilateral distal upper extremities. Skin biopsies are taken from erythematous papules and from a bulla.The histological features of the former are typical lichen planus changes, and the later is similar to bullous pemphigoid(BP). Direct immunofluorescence studies demonstrated linear deposition of IgG and C3 at the dermoepidermal junction of both the bullous and lichenoid lesions. Adiagnosis of LPP was established. We briefly review the literature on this uncommon entity.