Immunohematological problems in blood transfusion with patients with autoimmune hemolytic anemia

: The immunologic problems of blood transfusion of patients with antoimmune hemolytic anemia are discussed on the base of the authors' observations. They emerge and are mainly conditioned by the character and serological characteristic of autoantibodies (AAB) as well as by the presence of free iso-antibodies (erythro-, leuko- and thrombocyte-). The cold AAB conditioned the difficulties in blood groups determination, direct compatibility test and rarely of RH, where as the warm ones -- impede the determination of Rh and the selection of compatible blood for transfusion. The emerging of iso-antibodied complicates further the immunologic status of the patients. Owing to the characteristic specificity of AAB (against the widely found antigens -- nl, w, I, Pr, etc), the finding of compatible blood for transfusion proved practically to be extremely difficult. The forces hemotransfusion to be turned to only in case of vital indications.