Verapamil retard as a medication for the prevention of affective and schizoaffective psychosis relapses

: Twelve patients with affective and schisoaffective psychosis according to ICD-10 criteria were examined. In the earlier study, the patients displayed a resistance to verapamil of short duration action. After 4-year treatment, verapamil has been substituted for its retard dosage form--isoptin retard. Regarding antirelapse action, i.e., reduction of affective phases number and duration, increase of remissions and individual tolerability, isoptin retard proved to be superior. Retard form of verapamil is more convenient for usage. Recommendations for its use as a drug of choice for overcoming resistance to verapamil of short duration action are substantiated.