The bonding behavior of DP-Bioglass and bone tissue

There are many reports on the surface reactions of surface-active ceramics. A Ca-P-rich layer was found on the surface of these bioactive ceramics implanted in bone tissue, a chemical bond having been established between the mineralized matrix of the bone and the apatite layer of the bioactive ceramic. It has been reported that the direct bonding of bone to DP-Bioglass was due to the deposition and subsequent mineralization of organic bone matrix at the outer layer of the implant. Thus the strength of the bonding of DP-Bioglass with bone structure is expected to be such that it will overcome the fixing problems of joint replacement and improve the long-term performance of prostheses if the bioactive glass is coated onto alloys or stainless steel. In this study, DP-Bioglass was pressed into a steel disc, 6 mm in diameter and 5 mm thick, under a hydrostatic pressure of 270 MPa, and then sintered at 810 °C for 2 hours. The DP-Bioglass discs were implanted into the condyle area of mature male rabbits for 2, 4, 8, 16 and 32 weeks. The failure load, when an implant detached from the bone or when the bone itself broke, was measured by a push-out test. Sintered hydroxyapatite bioceramic was used in a control group and the results were compared with those using DP-Bioglass. The histological evaluation and histomorphometric investigation are described in the study to demonstrate the bonding behavior between DP-Bioglass and bone tissue.