Clinical evaluation of combined azacitidine and entinostat on the induction of fetal hemoglobin in patients with acute myeloid leukemias and myelodysplastic syndromes

Hemoglobinopathies are inherited disorders of globin chains leading to decreased production of hemoglobin (Hb), the most significant being sickle cell disease (SCD) and β-thalassemia. Expression of...