Phloeodictines A1-A7 and C1-C2, antibiotic and cytotoxic guanidine alkaloids from the new caledonian sponge, Phloeodictyon sp.

Abstract Phloeodictines A1-A7 ( 3a, 3b, 4a, 4b, 4c, 5a, 5b ) and phloeodictines C1-C2 ( 6a, 6b ), new antibacterial and cytotoxic guanidine alkaloids, have been isolated from the sponge Phloeodictyon sp. Their structures were established essentially by mass spectrometry utilizing B/E linked scanning and by 2D NMR experiments.