MP05-09 TRENDS IN EXTENDED-DURATION POSTOPERATIVE VENOUS THROMBOEMBOLISM PROPHYLAXIS FOLLOWING RADICAL CYSTECTOMY AMONG COMMERCIALLY INSURED PATIENTS IN THE UNITED STATES

INTRODUCTION AND OBJECTIVES:Venous thromboembolism (VTE) is an important cause of morbidity following radical cystectomy (RC) for bladder cancer. Accumulating evidence suggests that the risk of postoperative VTE may be lowered by discharging patients on extended-duration pharmacologic prophylaxis (EDPP). However, the degree to which this practice occurs in the United States has not been well studied. Herein, we evaluated temporal trends in outpatient VTE prophylaxis prescriptions following RC, and assessed patient as well as practice-level characteristics associated with receiving EDPP.METHODS:We used OptumLabs Data Warehouse, a national administrative claims database, to identify patients undergoing RC for MIBC from 2012-2017. Patients with initial hospital stay > 30 days or those on therapeutic dose anticoagulants were excluded. Rates of filled outpatient prescriptions for prophylactic dose low molecular weight heparin or fondaparinux following index hospitalization for RC were assessed, and rate over t...