Cryoglobulinemia complicated with multi-focal serous cavity hydrops: a case report and literature review

Cryoglobulinemia is a pathological condition in which the blood contains immunoglobulins that precipitate reversibly in the cold. Numerous factors and illnesses can lead to this condition, including Waldenstrom’s macroglobulinemia (WM). Here we describe a 75-year-old male with repetitive multiple serous cavity hydrops. We identified WM as the underlying cause. This case demonstrates the uncommon clinical manifestation of cryoglobulinemia with multiple serous cavity hydrops.