Oscillation and Optical Properties of Viruses and Other Pathogenic Microorganisms: A Review Article

The ability to detect rapidly, directly and selectively individual virus particles has the potential to significantly impact healthcare, since it could enable diagnosis at the earliest stages of replication within a host’s system. Simultaneous acquisition of the vibrational and electronic fingerprints of molecular systems of biological interest, at the interface between liquid media, or at the air /solid, air/liquid interfaces is difficult to achieve with conventional linear optical spectroscopies due to their rather poor sensitivity to the low number of molecules or their maladjustment to water environment (infrared absorption), at the exception of polarization modulation infrared absorption spectroscopy. The shift in energy gives information about the vibrational modes in the system. Infrared spectroscopy yields similar, but complementary information. Spontaneous scattering is typically very weak and as a result the main difficulty of this kind of spectroscopy is separating the weak inelastically scattered light from the intense Rayleigh scattered laser light. Viruses are assembled in the infected host cells of human, animals, or plants.