Pluripotent stem cells for brain tumor treatment

2014 
And to provide a new medical applications using pluripotent stem cells (Muse cells). The present invention includes a pluripotent stem cells SSEA-3 positive separated from mesenchymal tissue or cultured mesenchymal cells during biological provides a cell preparation for treating brain tumors. Cell preparation of the present invention, with respect to brain tumors in a subject, a Muse cells transfected with a suicide gene administered intravenously, Furthermore, by administering a prodrug that corresponds to the suicide gene, the Muse cells selected around brain tumors It was integrated, based on the mechanism of reducing the disappearance or proliferation of cells that constitute the brain by activation of prodrug due to expression of the suicide gene.
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