Antibacterial Total Phenolic Compounds from a Brown Alga Hizikia Fusiformis

Screening of potential antibacterial activities of total phenolic compounds isolated from a brown alga Hizikia fusiformis (Hary.) Okam. was performed using two antibacterial assays. Significant differences were observed both in total phenolic contents and antibacterial activities of extracts from H. fusiformis collected along the coast of East China Sea and South China Sea against Escherichia coli, Staphylococcus aureus, Bacillus subtilis, Enterobacter aerogenes and Shewanella sp. Methanol extracts from H. fusiformis collected in Zhoushan and Mazu exhibited the more antibacterial activities against E. coli. Ethanol extract from H. fusiformis collected in Naozhou had higher antibacterial activity against B. subtilis. In addition, the nitric oxide (NO) productions in inhibition process of bacterial growth with these fractions were determined by Griess reagent.