Synthesis and antitubercular activity of 6-chloro (unsubstituted)-2-methoxy-9-substituted acridine derivatives

Several analogues of the general formulae 2-methoxy-9-substituted acridine and 6-chloro-2-methoxy-9-substituted acridine were synthesized and evaluatedin vitro at 6.25 μg/mL againstM. tuberculosis H37Rv. Compounds15 and17 showed potential antitubercular activity with 100% inhibition to the virulent mycobacterium.