Increased Rates of Coronary Artery Calcium Score in Patients with NonFunctioning Adrenal Incidentalomas.

AIM We evaluated cardiovascular (CV) risk stratification for nonfunctioning adrenal incidentalomas (NFAIs) via the coronary-artery-calcium (CAC) score. Materials and methods: The participants were patients with an NFAI (n = 55). They were compared to patients with chest pain, a low-intermediate Framingham-risk score and a non-diagnostic treadmill-exercise test, which served as the control group (n = 49). Subsequently, the NFAI group was subdivided according to a CAC score of Results: Similar rates of traditional risk factors were observed between the NFAI and control groups, and lower low-density lipoprotein cholesterol rates were observed in the NFAI group. The CAC score was significantly higher for the NFAI group than the control group. Glucose, potassium, adrenocorticotropic-hormone and basal-cortisol levels were higher in those with a CAC score of ≥100. High-density-lipoprotein cholesterol, estimated glomerular filtration rate and ejection fraction (EF) were higher in those with a CAC score of Discussion: Patients with a low-intermediate CV risk profile and an NFAI have a higher risk of atherosclerosis, when compared to patients with a low-intermediate CV risk profile, but no NFAI. Conclusion: In cases where an NFAI exists, CAC score evaluation may be used to predict increased atherosclerosis, especially in patients of an older age with higher glucose and decreased EF.