MILD AND EFFICIENT METHOD FOR α-THIOCYANATION OF KETONES AND β-DICARBONYL COMPOUNDS USING BROMODIMETHYLSULFONIUM BROMIDE-AMMONIUM THIOCYANATE

An efficient and convenient method for α-thiocyanation of ketones and β-dicarbonyl compounds has been developed using a reagent combination of bromodimethylsulfonium bromide (BDMS) and ammonium thiocyanate in acetonitrile. The developed method is mild and gave good yield of the products at room temperature.