A Convenient Four-Step Synthesis of 1-{β-[3-(4-Methoxy-phenyl)Propoxy]-4- Methoxyphenethyl}-1H-Imidazole Hydrochloride as a Probing Tool for SOCE Assays

2016 
1-{β-[3-(4-Methoxy-phenyl)propoxy]-4-methoxyphenethyl}-1H-imidazole hydrochloride 7, or SKF-96365, was synthesized in four steps with an overall yield of 9%. The structure of 7 was confirmed by 1 H-, 13 C-NMR, HRMS, and elemental analysis. The intermediates 3 and 4 were also isolated and characterized by 1 H-, 13 C-NMR, and HRMS.
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