Effect of normal and defective vasectomy on the urinary 17-ketosteroid excretion rate and total pituitary gonadotrophin content in dogs.

The effect of normal and defective vasectomy on the urinary excretion rate of 17-ketosteroids and total pituitary gonadotropin levels were studied in the dog. The urinary excretion rates were not markedly changed at 90 180 and 360 days after the operation though there was a transitory but significant (p less than .05-.01) increase at 15 days. Pituitary gonadotropin content was higher in vasectomized animals than controls but was not markedly different among the different forms of vasectomy performed. There did not appear to be any correlation of the different vasectomy procedures with urinary 17-ketost eroid excretion or pituitary gonadotropin content.