A multi-aperture multi-tap image sensor for simultaneous multi-band SFDI and multi-exposure laser speckle contrast blood flow imaging

We propose a new image sensor based on multi-aperture optics and multi-tap charge modulators for simultaneous multi-band spatial frequency domain imaging (SFDI) and blood flow mapping by multi-exposure laser speckle contrast imaging (ME-LSCI). Wavelength-multiplexed imaging implemented by attaching different bandpass filters to each lens enables to perform multi-band SFDI and ME-LSCI simultaneously. A prototype camera for 4-band SFDI (568, 668, 734, 846nm) and single-band LSCI (780nm) was built based on a commercial CMOS camera with enhanced NIR sensitivity to demonstrate the concept and tested using a rat model of graded burns.