Method for detecting residual organic solvent in Favipiravir

The invention relates to a method for detecting residual organic solvent in Favipiravir, in particular to a method for detecting residual methanol, acetonitrile, dichloromethane, petroleum ether, ethyl acetate and dimethyl sulfoxide in Favipiravir at the same time through a gas chromatography. An external standard method is used for detecting the residual quantity of the six types of organic solvent in Favipiravir at the same time, wherein the chromatographic conditions are that the specification of a chromatographic column Agilent DB-1301 is 30 m * 0. 32 m * 0.25 microns, the temperature of the column is 180 DEG C, the temperature of a sample introduction opening is 200 DEG C, the detection temperature is 250 DEG C, carrier gas is N2, the split ratio is 10: 1, a sampling mode conducted through a headspace sampling method is adopted, the equilibrium time is 30 minutes, and the equilibrium temperature is 80 DEG C. The method for detecting residual methanol, acetonitrile, dichloromethane, petroleum ether, ethyl acetate and dimethyl sulfoxide in Favipiravir at the same time through the gas chromatography is high in sensitivity, good in repeatabilityand high in accuracy; the method is suitable for detecting the six types of residual organic solvent in Favipiravir.