TRK Inhibitors: Clinical Development of Larotrectinib

Munveer S. Bhangoo,Darren Sigal

TRK Inhibitors: Clinical Development of Larotrectinib

2019

Munveer S. Bhangoo
Darren Sigal

Purpose of Review In this review, we highlight the pre-clinical development, recent clinical studies, and future directions of larotrectinib in patients with NTRK fusion-positive tumors.

Keywords:

Immunology
Precision medicine
Trk receptor
Personalized medicine
Bioinformatics
Medicine
Cancer
Cancer research
Tyrosine kinase
Receptor
Tropomyosin
Tropomyosin receptor kinase A
Tropomyosin receptor kinase C
Tropomyosin receptor kinase B

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