Nanotechnology in non-cavitated lesions and tooth hypersensitivity

Abstract Noncavitated caries lesion is a demineralized lesion without evidence of cavitation. As the lesion progresses, the outer surface, which is in contact with plaque and is protected by the salivary pellicle, is exposed to cycles of demineralization and remineralization, and it regains some minerals (including fluoride) and becomes less prone to further demineralization. At this stage, the demineralization process can be reversed or arrested via remineralization products. Moreover, tooth sensitivity should only be used when the patient describes a significant increase in their dentine sensitivity, that is, hypersensitive dentine is supersensitive with respect to the patient’s previous experience. Nanotechnologies have favored our understanding of dental tissues at the nanoscale. This allows for understanding the genesis of tooth complex tissue which probes the structure of the protein and mineral components of the developing enamel matrix at the nano level, to replicate this process as biomimetic remineralizations and regeneration.