Research on Cancerization Tendency of Precancerous Lesion of Gastric Cancer and Its Laws

Objective:To study syndrome developing types of canceration cases with precancerous lesion of gastric cancer(PLGC)from Traditional Chinese Medicine syndrome.Methods:Adopting multi-center collaboration,324 cases of PLGC with Xu-Shi correlation syndrome were studied by setting up five observation ports for two years clinical pursuit.At equal pace,tumor supplied group of factors(TSGF)and carcino-embryonic antigen(CEA)were detected.Results:Among seven types of Xu-Shi correlation syndrome of 324 cases,canceration cases were 29,accounted for 9%.Three types of syndrome of higher cancer rate were damp-heat accumulating stomach combining/concurrent asthenia-cold in the spleen and stomach,accounted for 16.7%;stagnation in stomach collaterals combining/concurrent asthenia of both qi and yin,accounted for 13.2%;stagnation of liver and stomach qi combining/concurrent asthenia-cold in the spleen and stomach,accounted for 8%.Detection of TSGF showed that the first two types had higher value.The syndromes of canceration cases half a year before canceration showed excess and deficiency concurrent,and deficient syndrome involving in qi-blood and kidney deficiency accounted for 48%.Conclusion:PLGC canceration syndromes have polymorphism of excess and deficiency concurrent and characteristic of deficiency involving in qi-blood,kidney-yin and kidney-yang.