Frequency of metabolic syndrome in Behcets disease and its relation with Behcets disease activity

Coronary artery disease is the most common cause of death and on time diagnosis and control is essential in improving health and increased longevity. It has been recognized that autoimmune mechanisms play a major role in the pathogenesis of atherosclerosis. In many cases, metabolic syndrome increases the risk of coronary artery disease, stroke and diabetes. The prevalence of this syndrome is high and in most cases it does not matter. The aim of this study was to investigate the prevalence of metabolic syndrome in Behcet's disease and its association with Behcet's disease intensity. In a cross-sectional and descriptive-analytic study that performed in internal medicine department of Tabriz University of Medical Sciences on patients with Behcet's disease, the prevalence of metabolic syndrome in Behcet's disease and its association with Behcet's disease intensity evaluated. 41 of patients (74.5%) were male and 14 of them (35.5%) were female. Mean age of patients was 38.80 ± 10.18 year. Metabolic syndrome was found in 14 patients (25.5%) of the studied patients. The prevalence of metabolic syndrome in male patients with Behcet's disease was 24.4% in female patients with Behcet's disease was 28.6% that prevalence of metabolic syndrome was higher in female patients than male patients. In our study, prevalence rate of metabolic syndrome in patients with age less than 40 year was 17.24% and prevalence rate of metabolic syndrome in patients with age less than 40 year was 34.6% that prevalence rate of metabolic syndrome was increase with increase of patients age. Significant difference in eye score of patients at patients with and without metabolic syndrome (P=0.326). Significant difference in non-eye score of patients at patients with and without metabolic syndrome (P=0.328). Our results and various studies results suggest that in inflammatory diseases such as Behcet's, rheumatoid arthritis, psoriasis and IBD prevalence of metabolic syndrome is higher than other members of society, Note that this requires more and better screening period, the patients in terms of cardiovascular disease and diabetes for more highlights. Significant correlation was not found between Behcet's disease intensity and metabolic syndrome.