Topical ALA-Photodynamic Therapy for Acne Can Induce Apoptosis of Sebocytes and Down-regulate Their TLR-2 and TLR-4 Expression

Eugene Jeong,Ji Won Hong,Jung-Ah Min,Dong Won Lee,Mi Yeung Sohn,Weon-Ju Lee,Jun Young Lee,Young Min Park

Topical ALA-Photodynamic Therapy for Acne Can Induce Apoptosis of Sebocytes and Down-regulate Their TLR-2 and TLR-4 Expression

2011

Eugene Jeong
Ji Won Hong
Jung-Ah Min
Dong Won Lee
Mi Yeung Sohn
Weon-Ju Lee
Jun Young Lee
Young Min Park

Conclusion: Our results demonstrate that apoptosis of the sebaceous glands is associated with improvement of acne by PDT. PDT has shown to down-regulate TLR-2 and TLR-4 expression in the sebaceous glands and epidermis of acne

Keywords:

Dermatology
Alternative medicine
Acne
Apoptosis
Cancer research
Photodynamic therapy
Medicine
Biopsy
TUNEL assay
Immunohistochemistry
Pathology
Epidermis (botany)
Receptor

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