The biological characters of invasive pituitary adenoma of human

Objectives: Invasiveness is the feature of malignant tumor,which some pituitary adenomas have.The DNA ploidy and the proliferation ability of invasive adenoma cells were studied. Methods: Pituitary adenoma cells were assayed by Flow Cytometer and Image Cytometer. Results: Invasiveness of pituitary adenoma correlated with the proportion of abnormal DNA ploidy cells. Conclusions: From the DNA ploidy of invasive pituitary adenoma,we could conclude that invasive pituitary adenoma developed malignantly.