Screening of Aerial Parts of the Plant Clerodendrum paniculatum Linn for Anti-Convulsant Activity

The present study was undertaken for investigating and validating the traditional claims of Clerodendrum paniculatum Linn for its anti-convulsant activity. Clerodendrum paniculatumlinn belongs to verbenacae family. Ethno medical importance of various species of Clerodendrum genus has been reported in various indigenous systems of medicines and folk medicines. It is used as a medicine for the treatment of sore eyes, urinary tract, gonorrhoea and kidney problems. However pharmacological properties of plants have not yet been extensively studied, it is therefore thought worthwhile to study about the unrevealed properties of this plant. The aerial parts of plant are used for preparing extraction using ethyl acetate, petroleum ether and aqueous as a solvent. Shade dried, powdered (40 mesh size) leaves of Clerodendrum paniculatum Linn were extracted with ethyl acetate, petroleum ether and macerated with distilled water. On using solvent extraction phytochemical screening was analyzed, it reveals the presence of flavanoids, tannins, glycosides, saponins, and terpenoids like compounds. Anti-convulsant activity of ethyl acetate extract shows significant activity comparable with standard drug, Phyntoin. Petroleum ether and aqueous extracts shows little anti-convulsant activity.